People have been trying to make malaria vaccines for over 100 years. Well over 100 vaccines have gone into clinical trials in people. Very, very few have worked to any degree.
Malaria is not a virus, it’s not a bacterium. It’s a protozoan parasite, some thousands of times larger than a typical virus. A good measure of that is how many genes it has. Covid has 13, malaria has about 5,500. This is one of the reasons that malaria is super complex.
With the help of the revolutionary new R21/Matrix vaccine the disease could be eradicated by 2040 (as claimed).
Perhaps anti-vaxx missionaries can do for malaria what christian missionaries do for HIV?
I can totally imagine them setting up camps, teaching people to just “believe in their immune system”, discouraging proven medicine in the process.