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Cake day: June 18th, 2023

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  • Ah, did you look at the second link?

    It is somewhat more difficult to understand the “chromosome tangling hypothesis.” We recently found that asbestos fibers including crocidolite are actively taken up by several different kinds of cultured cells. Furthermore, those fibers enter both the cytoplasm and the nucleus. In this situation, asbestos fibers may tangle with chromosomes when cells divide. Whether there is a specificity of tangling for any chromosomal region is the next question to be addressed.

    Which comes with this image:

    Granted there isn’t a lot of experimental evidence for this (that I can find, anyway), but it makes sense that tiny little silicate needles that get absorbed by the nucleus interfere with the chromosomes both mechanically and chemically.

    I also found this:

    A normal (A) and an abnormal (B) anaphase from asbestos-treated Syrian hamster embryo cells. Note the asbestos fibers (arrows), some of which appear to be associated with displaced chromosomes (arrowheads) in the abnormal anaphase. Reproduced from Hesterberg and Barrett (42) with permission.

    Asbestos fibers are observed in the mitotic cells and appear, in some cases, to interact directly with the chromosomes. From these studies we propose that the physical interaction of asbestos fibers with the chromosomes or structural proteins of the spindle apparatus causes missegregation of chromosomes during mitosis, resulting in aneuploidy.

    https://www.researchgate.net/figure/A-normal-A-and-an-abnormal-B-anaphase-from-asbestos-treated-Syrian-hamster-embryo_fig1_20488222



  • If I remember correctly, one of the biggest problems was the transportation issue, which no one had a solution for. How exactly do you safely transfer several tons of nuclear waste from, say, Shearon Harris to Yucca Mountain? that’s a very long train route. And you want to do this on a recurring basis? from several different locations around the country?

    How exactly are you going to convince the states in between that they should permit you to transport nuclear waste across their borders, repeatedly? Who is going to provide security for all of this nuclear waste while it’s in transit? Who is going to accept liability for any accidents that occur, and who is going to handle the PR when a truckload of irradiated water gets dumped in some neighborhood?

    Good luck getting anyone who even wants to explore establishing those arrangements as their full-time job. “Yes, I brokered the agreement for transporting radioactive material that resulted in a half-ton of waste being spread across ten backyards and an elementary school playground just outside of Birmingham.” Sounds like career suicide, and maybe not career suicide.